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pubmed-article:15641091pubmed:abstractTextTreatment of rheumatoid arthritis (RA) with tumor necrosis factor (TNF) antagonists is highly effective, but their mechanisms of action are not completely clear. Since anti-TNF therapy induces a decrease in synovial cellularity, this study focused on the modulation of RA synovial apoptosis following treatment with either soluble TNF receptor (etanercept) or TNF chimeric monoclonal antibody (infliximab).lld:pubmed
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pubmed-article:15641091pubmed:articleTitleEvidence that anti-tumor necrosis factor therapy with both etanercept and infliximab induces apoptosis in macrophages, but not lymphocytes, in rheumatoid arthritis joints: extended report.lld:pubmed
pubmed-article:15641091pubmed:affiliationRheumatology Research Laboratory, CMM L8:04, Karolinska University Hospital, S-171 76 Stockholm, Sweden. Anca.Catrina@cmm.ki.selld:pubmed
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