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rdf:type |
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lifeskim:mentions |
umls-concept:C0003864,
umls-concept:C0017337,
umls-concept:C0022417,
umls-concept:C0024518,
umls-concept:C0205164,
umls-concept:C0521117,
umls-concept:C0597336,
umls-concept:C0851285,
umls-concept:C1549781,
umls-concept:C1709456,
umls-concept:C1883709
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pubmed:issue |
1
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pubmed:dateCreated |
2005-1-13
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pubmed:abstractText |
To construct rats congenic for the chromosome 2 arthritis-regulatory quantitative trait locus Cia10, originally identified in a (DA x ACI)F(2) intercross rat strain that had been assessed for collagen-induced arthritis (CIA), and to determine the effect of this congenic interval on arthritis severity, joint histologic structure, and cytokine transcription in rats with pristane-induced arthritis (PIA).
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
322-32
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:15641042-Animals,
pubmed-meshheading:15641042-Animals, Congenic,
pubmed-meshheading:15641042-Arthritis, Experimental,
pubmed-meshheading:15641042-Body Weight,
pubmed-meshheading:15641042-Chromosomes, Mammalian,
pubmed-meshheading:15641042-DNA, Complementary,
pubmed-meshheading:15641042-Extremities,
pubmed-meshheading:15641042-Exudates and Transudates,
pubmed-meshheading:15641042-Female,
pubmed-meshheading:15641042-Interleukin-1,
pubmed-meshheading:15641042-Joints,
pubmed-meshheading:15641042-Major Histocompatibility Complex,
pubmed-meshheading:15641042-Male,
pubmed-meshheading:15641042-Protein Tyrosine Phosphatase, Non-Receptor Type 22,
pubmed-meshheading:15641042-Protein Tyrosine Phosphatases,
pubmed-meshheading:15641042-Quantitative Trait Loci,
pubmed-meshheading:15641042-RNA, Messenger,
pubmed-meshheading:15641042-Rats,
pubmed-meshheading:15641042-Rats, Inbred Strains,
pubmed-meshheading:15641042-Severity of Illness Index,
pubmed-meshheading:15641042-Synovial Membrane,
pubmed-meshheading:15641042-Terpenes,
pubmed-meshheading:15641042-Tumor Necrosis Factor-alpha
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pubmed:year |
2005
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pubmed:articleTitle |
The non-major histocompatibility complex quantitative trait locus Cia10 contains a major arthritis gene and regulates disease severity, pannus formation, and joint damage.
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pubmed:affiliation |
Laboratory of Experimental Rheumatology, R.S. Boas Center for Genomics and Human Genetics, North Shore-Long Island Jewish Research Institute, 350 Community Drive, Manhasset, NY 11030, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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