Linked Life Data

15639837

Source:http://linkedlifedata.com/resource/pubmed/id/15639837

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2005-1-10
pubmed:abstractText
Association of restriction fragment length polymorphism (RFLP) of the parathyroid hormone (PTH) gene with bone mineral density (BMD) was explored in unrelated postmenopausal women who live in Beijing. One hundred and eighty-five healthy, unrelated postmenopausal women were selected and whose BMDs were measured by dual-energy X-ray absorptioemetry (DEXA). The genotypes of PTH were detected with RFLP method. The frequency of each genotype was bb 7.56%bBb 28.11% and BB 64.32% respectively. ANOVA analysis showed that the forearm BMD was associated with PTH gene. The women with BB genotype have higher BMD than Bb and bb ones. Logistic regression analysis indicated that there was a significant difference between normal and osteoporosis women with bb genotype (P<0.001). This result indicated that B allele might have some protective effects to bone mass loss.
pubmed:language
chi
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Mar
pubmed:issn
0253-9772
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
133-6
pubmed:dateRevised
2006-11-15
pubmed:year
2003
pubmed:articleTitle
[Association study of RFLP of parathyroid hormone gene and bone mineral density in postmenopausal women].
pubmed:affiliation
National Research Institute for Family Planning, Beijing 100081, China, lid719@263.cn
pubmed:publicationType
Journal Article, English Abstract