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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2005-1-5
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pubmed:abstractText |
Alcohol consumption exacerbates liver injury in chronic hepatitis C, and enhanced mitochondrial oxidative stress is one possible mechanism. The aim of this study was to determine whether hepatitis C virus core protein and alcohol-inducible cytochrome P450 2E1 contribute to reactive oxygen species production and cytotoxicity in human hepatoma cells.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0016-5085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
128
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
96-107
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15633127-Alcohols,
pubmed-meshheading:15633127-Carcinoma, Hepatocellular,
pubmed-meshheading:15633127-Cell Death,
pubmed-meshheading:15633127-Cell Line, Tumor,
pubmed-meshheading:15633127-Chronic Disease,
pubmed-meshheading:15633127-Cytochrome P-450 CYP2E1,
pubmed-meshheading:15633127-Ethanol,
pubmed-meshheading:15633127-Glutathione,
pubmed-meshheading:15633127-Hepatitis C,
pubmed-meshheading:15633127-Humans,
pubmed-meshheading:15633127-Liver Neoplasms,
pubmed-meshheading:15633127-Mitochondria,
pubmed-meshheading:15633127-Models, Biological,
pubmed-meshheading:15633127-Oxidative Stress,
pubmed-meshheading:15633127-Reactive Oxygen Species,
pubmed-meshheading:15633127-Tumor Necrosis Factor-alpha,
pubmed-meshheading:15633127-Viral Core Proteins
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pubmed:year |
2005
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pubmed:articleTitle |
Hepatitis C virus core protein, cytochrome P450 2E1, and alcohol produce combined mitochondrial injury and cytotoxicity in hepatoma cells.
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pubmed:affiliation |
Department of Neuroscience and Cell Biology, University of Texas Medical Branch at Galveston, 301 University Boulevard, Galveston, TX 77555-0632, USA
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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