Source:http://linkedlifedata.com/resource/pubmed/id/15633094
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2005-1-5
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pubmed:abstractText |
The impact of demographic characteristics, phase of the menstrual cycle, use of hormonal contraceptives, and concomitant lower genital-tract infections on cervicovaginal inflammatory cells was assessed in 967 women, 654 of whom were infected with human immunodeficiency virus type 1 (HIV-1). Cervicovaginal lavage (CVL) fluid was evaluated for total white blood cell (WBC), polymorphonuclear leukocyte, and monocyte counts. HIV-1 infection was not associated with statistically significant differences in numbers of inflammatory cells in CVL fluid except in 1 group--HIV-1-infected women with Chlamydia trachomatis infection had a 0.43 log(10) higher WBC count than their HIV-uninfected, chlamydia-positive counterparts (P=.04). Younger age and use of progesterone-based hormonal contraceptives were independently associated with increased numbers of inflammatory cells in CVL fluid. A 0.15-0.2 log(10) increase in inflammatory cells was seen in black versus white and Hispanic women after adjustment for known potential confounders. Progesterone-based contraceptives, younger age, and race have an independent effect on cervicovaginal inflammatory cells.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0022-1899
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pubmed:author |
pubmed-author:DuerrAnn CAC,
pubmed-author:GhanemKhalil GKG,
pubmed-author:HIV Epidemiology Research Study Group,
pubmed-author:JamiesonDenise JDJ,
pubmed-author:KleinRobert SRS,
pubmed-author:MayerKenneth HKH,
pubmed-author:RompaloAnne MAM,
pubmed-author:ShahNinaN,
pubmed-author:SobelJack DJD,
pubmed-author:WarrenD LDL
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
191
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
358-66
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15633094-Adolescent,
pubmed-meshheading:15633094-Adult,
pubmed-meshheading:15633094-Cervix Uteri,
pubmed-meshheading:15633094-Female,
pubmed-meshheading:15633094-Genital Diseases, Female,
pubmed-meshheading:15633094-Gonadal Steroid Hormones,
pubmed-meshheading:15633094-HIV Infections,
pubmed-meshheading:15633094-HIV-1,
pubmed-meshheading:15633094-Humans,
pubmed-meshheading:15633094-Inflammation,
pubmed-meshheading:15633094-Menstrual Cycle,
pubmed-meshheading:15633094-Middle Aged,
pubmed-meshheading:15633094-Sexually Transmitted Diseases,
pubmed-meshheading:15633094-Vagina
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pubmed:year |
2005
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pubmed:articleTitle |
Influence of sex hormones, HIV status, and concomitant sexually transmitted infection on cervicovaginal inflammation.
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pubmed:affiliation |
Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA. kghanem@jhmi.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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