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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
24
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pubmed:dateCreated |
2004-12-29
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pubmed:abstractText |
Human reovirus type 3 has been proposed to kill cancer cells with an activated Ras signaling pathway. The purpose of this study was to investigate the efficacy of reovirus in immunocompetent glioma animal models and safety/toxicity in immunocompetent animals, including nonhuman primates.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:BrasherPenny M APM,
pubmed-author:CoffeyMattM,
pubmed-author:DyckRichardR,
pubmed-author:FonsecaKevinK,
pubmed-author:ForsythPeter APA,
pubmed-author:GeorgeDavidD,
pubmed-author:HamiltonMarkM,
pubmed-author:JohnstonRandal NRN,
pubmed-author:LeePatrick W KPW,
pubmed-author:LunXueqingX,
pubmed-author:MuzikHuongH,
pubmed-author:NishikawaSandra GSG,
pubmed-author:PalmerCheryl AnnCA,
pubmed-author:RewcastleN BerryNB,
pubmed-author:SengerDonna LDL,
pubmed-author:ShiZhong QiaoZQ,
pubmed-author:StewartDougD,
pubmed-author:ThompsonBradB,
pubmed-author:WilcoxM ElizabethME,
pubmed-author:YangWen QingWQ
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
8561-76
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15623640-Animals,
pubmed-meshheading:15623640-Brain Neoplasms,
pubmed-meshheading:15623640-Encephalitis,
pubmed-meshheading:15623640-Female,
pubmed-meshheading:15623640-Glioblastoma,
pubmed-meshheading:15623640-Green Fluorescent Proteins,
pubmed-meshheading:15623640-Humans,
pubmed-meshheading:15623640-Immunoglobulin G,
pubmed-meshheading:15623640-In Situ Hybridization,
pubmed-meshheading:15623640-Macaca fascicularis,
pubmed-meshheading:15623640-Male,
pubmed-meshheading:15623640-Mammalian orthoreovirus 3,
pubmed-meshheading:15623640-Maze Learning,
pubmed-meshheading:15623640-Models, Animal,
pubmed-meshheading:15623640-Neutralization Tests,
pubmed-meshheading:15623640-Rats,
pubmed-meshheading:15623640-Rats, Inbred F344,
pubmed-meshheading:15623640-Rats, Nude,
pubmed-meshheading:15623640-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:15623640-Survival Rate,
pubmed-meshheading:15623640-Tumor Cells, Cultured
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pubmed:year |
2004
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pubmed:articleTitle |
Efficacy and safety evaluation of human reovirus type 3 in immunocompetent animals: racine and nonhuman primates.
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pubmed:affiliation |
Departments of Oncology and Clinical Neurosciences, University of Calgary, and Tom Baker Cancer Centre, Calgary, Alberta, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Evaluation Studies
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