15597579

Source:http://linkedlifedata.com/resource/pubmed/id/15597579

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0040648, umls-concept:C1260873
pubmed:issue	6
pubmed:dateCreated	2004-12-15
pubmed:abstractText	Previous immunohistochemistry studies have shown that the transcription factor, Egr-1, is increased in human atherosclerotic lesions but is absent from the normal adjacent aortic wall. The hypothesis was investigated that Egr-1 is also increased in calcified heart valve cusps because of the unique presence in these tissues of proteins known to be regulated by Egr-1, such as tenascin C (TN-C).
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9312096
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Collagen, http://linkedlifedata.com/resource/pubmed/chemical/EGR1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Early Growth Response Protein 1, http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Protein Kinase C, http://linkedlifedata.com/resource/pubmed/chemical/Tenascin
pubmed:status	MEDLINE
pubmed:month	Nov
pubmed:issn	0966-8519
pubmed:author	pubmed-author:ClarkJocelynJ, pubmed-author:ConnollyJeanne MJM, pubmed-author:DeFeliceSuzanneS, pubmed-author:Ghazvini-BoroujerdiMarjanM, pubmed-author:HazelwoodSenatorS, pubmed-author:JianBoB, pubmed-author:LevyRobert JRJ, pubmed-author:MEOLL, pubmed-author:NarulaNavneetN, pubmed-author:PalmatoryElizabethE
pubmed:issnType	Print
pubmed:volume	13
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	894-903
pubmed:dateRevised	2007-11-15
pubmed:meshHeading	pubmed-meshheading:15597579-Aged, pubmed-meshheading:15597579-Aged, 80 and over, pubmed-meshheading:15597579-Animals, pubmed-meshheading:15597579-Aortic Valve, pubmed-meshheading:15597579-Aortic Valve Stenosis, pubmed-meshheading:15597579-Calcinosis, pubmed-meshheading:15597579-Cardiomyopathies, pubmed-meshheading:15597579-Cell Proliferation, pubmed-meshheading:15597579-Cells, Cultured, pubmed-meshheading:15597579-Collagen, pubmed-meshheading:15597579-Early Growth Response Protein 1, pubmed-meshheading:15597579-Enzyme Inhibitors, pubmed-meshheading:15597579-Female, pubmed-meshheading:15597579-Humans, pubmed-meshheading:15597579-Male, pubmed-meshheading:15597579-Protein Kinase C, pubmed-meshheading:15597579-Sheep, pubmed-meshheading:15597579-Tenascin, pubmed-meshheading:15597579-Up-Regulation
pubmed:year	2004
pubmed:articleTitle	Transcription factor Egr-1 in calcific aortic valve disease.
pubmed:affiliation	Cardiology Research Laboratory, Children's Hospital of Philadelphia, Philadelphia, PA 19104-4318, USA.
pubmed:publicationType	Journal Article, Comparative Study