Linked Life Data

1559153

Source:http://linkedlifedata.com/resource/pubmed/id/1559153

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1992-5-14
pubmed:abstractText
We present three patients with a nontraumatic cervical anterior spinal artery syndrome, two of whom developed painful burning dysaesthesias below the level of spinal cord lesion, refractory to opiate, anticonvulsant and tricyclic antidepressant therapy. Quantitative sensory testing and neurophysiological assessment showed absence of pain and temperature sensation below the level of the lesion, with preservation of light touch, vibratory and position sensibilities and cortical somatosensory evoked potentials in all three patients. Dysaesthesias in both affected patients were exacerbated by somatosensory input attributed to intact posterior column function. Posterior column electrical stimulation worsened the dysaesthesias in one affected patient, and was ineffective in the other. Both patients affected with dysaesthesias showed significant improvement in motor function and developed clinical spasticity, while the third patient developed neither dysaesthesias nor spasticity, but remained flaccid without motor improvement, suggesting a more complete lesion of anterolateral spinal pathways. These cases illustrate that lesions of the anterolateral spinal cord may lead to the development of dysaesthesias, perhaps related in part to selective neospinothalamic deafferentation and preservation of the posterior columns.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0006-8950
pubmed:author
pubmed:issnType
Print
pubmed:volume
115 Pt 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
189-98
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Sensory abnormalities and dysaesthesias in the anterior spinal artery syndrome.
pubmed:affiliation
Department of Neurology, University of Texas Health Science Center, Houston.
pubmed:publicationType
Journal Article, Case Reports, Research Support, Non-U.S. Gov't