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pubmed-article:15579016pubmed:abstractTextNatural and synthetic indolocarbazole compounds have triggered considerable interest since the discovery in 1986 of the inhibitory properties of staurosporine toward protein kinase C (PKC). Later, it has been shown that indolocarbazole compounds may inhibit various kinases, such as cyclin dependent-kinases and/or topoisomerase I, someones behave only as DNA intercalators. In this review are presented various indolocarbazole compounds bearing a sugar moiety and their biological targets. The relevance of these targets to develop indolocarbazole compounds as potential antitumor agents is discussed.lld:pubmed
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pubmed-article:15579016pubmed:authorpubmed-author:PrudhommeMich...lld:pubmed
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pubmed-article:15579016pubmed:articleTitleBiological targets of antitumor indolocarbazoles bearing a sugar moiety.lld:pubmed
pubmed-article:15579016pubmed:affiliationLaboratoire SEESIB, UMR 6504 CNRS, Université Blaise Pascal, 24, Avenue des Landais, 63177 Aubiere, France. mprud@chimie.univ-bpclermont.frlld:pubmed
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