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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2004-12-3
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|
pubmed:abstractText |
Anorectal melanoma (AM) is a rare but highly malignant tumor, displaying histologic and immunohistochemical features very similar to cutaneous melanoma (CM). Because BRAF mutations were recently identified in the majority of CM and nevi, we investigated AM for BRAF mutations and mutations of NRAS , an additional component of the MAPK-signalling pathway.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0016-5085
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pubmed:author |
pubmed-author:BennerAxelA,
pubmed-author:DeichmannMartinM,
pubmed-author:GasslerNikolausN,
pubmed-author:HelmkeBurkhard MBM,
pubmed-author:Herold-MendeChristelC,
pubmed-author:LyerStefanS,
pubmed-author:MollenhauerJanJ,
pubmed-author:OttoHerwart FHF,
pubmed-author:PoustkaAnnemarieA,
pubmed-author:ThomeMarianneM,
pubmed-author:WahlWolfgangW
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pubmed:issnType |
Print
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pubmed:volume |
127
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1815-20
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15578519-Aged,
pubmed-meshheading:15578519-Aged, 80 and over,
pubmed-meshheading:15578519-Anus Neoplasms,
pubmed-meshheading:15578519-DNA, Neoplasm,
pubmed-meshheading:15578519-DNA Mutational Analysis,
pubmed-meshheading:15578519-Humans,
pubmed-meshheading:15578519-Male,
pubmed-meshheading:15578519-Melanoma,
pubmed-meshheading:15578519-Middle Aged,
pubmed-meshheading:15578519-Polymerase Chain Reaction,
pubmed-meshheading:15578519-Proto-Oncogene Proteins B-raf,
pubmed-meshheading:15578519-Rectal Neoplasms,
pubmed-meshheading:15578519-Skin Neoplasms
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pubmed:year |
2004
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pubmed:articleTitle |
BRAF mutations distinguish anorectal from cutaneous melanoma at the molecular level.
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pubmed:affiliation |
Institute of Pathology, University of Heidelberg, D-69210 Heidelberg, Germany. Burkhard_Helmke@med.uni-heidelberg.de
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pubmed:publicationType |
Journal Article,
Case Reports
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