Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2004-11-29
pubmed:abstractText
Lymphocyte depletion is a commonly used approach in clinical renal transplantation as part of standard induction immunosuppression therapy. It is also increasing being incorporated into new approaches aimed at inducing transplantation tolerance. While the theoretical basis for eliminating alloreactive T cells as a means to prevent rejection and induce tolerance is sound, new evidence suggests that global non-specific deletion may, by promoting the development of memory T cells, actually present a barrier to tolerance induction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0302-5144
pubmed:author
pubmed:issnType
Print
pubmed:volume
146
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
65-72
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Lymphocyte depletion as a barrier to immunological tolerance.
pubmed:affiliation
University of Pennsylvania, Philadelphia, PA 19104, USA.
pubmed:publicationType
Journal Article, Comparative Study, Review