Linked Life Data

15552423

Source:http://linkedlifedata.com/resource/pubmed/id/15552423

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
19
pubmed:dateCreated
2004-11-19
pubmed:abstractText
Extensive use of models in pharmacology, in physiology and in radiotherapy raises some questions on the nature and utility of models in general and of compartmental models in particular. In this paper I will define in a simple and logical way a set of useful pharmacokinetic parameters and show how their estimation depends on the assumed model. A special problem arises when some parameters are not identifiable; in that case I will show how it is possible to determine a range for them. Two examples are used to illustrate how to compute the value of the identifiable parameters and the range of the non-identifiable ones, when the available experimental data are not sufficient to identify a model.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0031-9155
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
49
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
4657-76
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
On the use of pharmacokinetic models.
pubmed:affiliation
Department of Pharmaceutics, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.
pubmed:publicationType
Journal Article