Source:http://linkedlifedata.com/resource/pubmed/id/15551925
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
17
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pubmed:dateCreated |
2004-11-19
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pubmed:abstractText |
Eleven dogs were used in a trial to find a suitable dose of dexamethasone for an oral dexamethasone suppression test for the diagnosis of hyperadrenocorticism. Basal urinary corticoid:creatinine ratios were established in all 11 and then groups of seven were given oral doses of 0.02, 0.01 or 0.0075 mg dexamethasone/kg bodyweight and urine samples were collected at two-hour intervals from 08.00 to 22.00. The doses of 0.02 and 0.01 mg/kg consistently suppressed their urinary corticoid:creatinine ratios measured at 16.00 by a mean of more than 50 per cent and those of individual dogs to less than 1.0 x 10(-6), whereas the dose of 0.0075 mg/kg did not.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0042-4900
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
23
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pubmed:volume |
155
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
518-21
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15551925-Administration, Oral,
pubmed-meshheading:15551925-Adrenal Cortex Function Tests,
pubmed-meshheading:15551925-Animals,
pubmed-meshheading:15551925-Creatinine,
pubmed-meshheading:15551925-Dexamethasone,
pubmed-meshheading:15551925-Dogs,
pubmed-meshheading:15551925-Dose-Response Relationship, Drug,
pubmed-meshheading:15551925-Female,
pubmed-meshheading:15551925-Glucocorticoids,
pubmed-meshheading:15551925-Male,
pubmed-meshheading:15551925-Reference Values
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pubmed:year |
2004
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pubmed:articleTitle |
Urinary corticoid:creatinine ratios in healthy pet dogs after oral low-dose dexamethasone suppression tests.
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pubmed:affiliation |
Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, PO Box 80154, 3508 TD, The Netherlands.
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pubmed:publicationType |
Journal Article,
Comparative Study
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