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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2004-11-19
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pubmed:abstractText |
We demonstrated that highly active antiretroviral therapy (HAART) increases the toxic effect of cyclophosphamide, vincristine, doxorubicin (DOX) and prednisone (CHOP) in HIV-patients with non-Hodgkin's lymphoma (NHL). To ascertain the cause of increased toxicity, we investigated the pharmacokinetics of DOX in HIV-patients with NHL treated with CHOP with and without HAART.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0923-7534
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1805-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15550586-Adult,
pubmed-meshheading:15550586-Antibiotics, Antineoplastic,
pubmed-meshheading:15550586-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:15550586-Antiretroviral Therapy, Highly Active,
pubmed-meshheading:15550586-Area Under Curve,
pubmed-meshheading:15550586-Cross-Over Studies,
pubmed-meshheading:15550586-Cyclophosphamide,
pubmed-meshheading:15550586-Doxorubicin,
pubmed-meshheading:15550586-Drug Interactions,
pubmed-meshheading:15550586-Female,
pubmed-meshheading:15550586-HIV Infections,
pubmed-meshheading:15550586-Humans,
pubmed-meshheading:15550586-Lymphoma, AIDS-Related,
pubmed-meshheading:15550586-Lymphoma, Non-Hodgkin,
pubmed-meshheading:15550586-Male,
pubmed-meshheading:15550586-Middle Aged,
pubmed-meshheading:15550586-Prednisone,
pubmed-meshheading:15550586-Vincristine
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pubmed:year |
2004
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pubmed:articleTitle |
Effect of highly active antiretroviral therapy (HAART) on pharmacokinetics and pharmacodynamics of doxorubicin in patients with HIV-associated non-Hodgkin's lymphoma.
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pubmed:affiliation |
Experimental and Clinical Pharamcology Unit, National Cancer Institute, Aviano, Italy. gtoffoli@cro.it
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
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