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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
24
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pubmed:dateCreated |
2004-11-19
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pubmed:abstractText |
A new class of NO-donor phenol derivatives is described. The products were obtained by joining appropriate phenols with either nitrooxy or 3-phenylsulfonylfuroxan-4-yloxy moieties. All the compounds proved to inhibit the ferrous salt/ascorbate induced lipidic peroxidation of membrane lipids of rat hepatocytes. They were also capable of dilating rat aorta strips precontracted with phenylephrine.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0960-894X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
20
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5971-4
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:15546710-Animals,
pubmed-meshheading:15546710-Antioxidants,
pubmed-meshheading:15546710-Aorta,
pubmed-meshheading:15546710-Arteriosclerosis,
pubmed-meshheading:15546710-Ascorbic Acid,
pubmed-meshheading:15546710-Ferrous Compounds,
pubmed-meshheading:15546710-Hepatocytes,
pubmed-meshheading:15546710-Hypolipidemic Agents,
pubmed-meshheading:15546710-Lipid Peroxidation,
pubmed-meshheading:15546710-Male,
pubmed-meshheading:15546710-Membrane Lipids,
pubmed-meshheading:15546710-Nitric Oxide Donors,
pubmed-meshheading:15546710-Phenols,
pubmed-meshheading:15546710-Phenylephrine,
pubmed-meshheading:15546710-Rats,
pubmed-meshheading:15546710-Rats, Wistar,
pubmed-meshheading:15546710-Structure-Activity Relationship,
pubmed-meshheading:15546710-Thiobarbituric Acid Reactive Substances
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pubmed:year |
2004
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pubmed:articleTitle |
Development of a new class of potential antiatherosclerosis agents: NO-donor antioxidants.
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pubmed:affiliation |
Dipartimento di Scienza e Tecnologia del Farmaco, Via P. Giuria 9, I-10125 Torino, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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