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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2004-11-15
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pubmed:abstractText |
Chemotherapy is suspected of having an effect on the generation of phenotypical heterogeneity and the development of drug resistance in tumors. Recurrent gliomas feature drug resistance as well as greater invasive growth than original tumors. The authors investigated phenotypical changes in invasion observed in 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-resistant sublines of the 9L rat gliosarcoma.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0022-3085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
101
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
826-31
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15540922-Animals,
pubmed-meshheading:15540922-Antineoplastic Agents, Alkylating,
pubmed-meshheading:15540922-Brain Neoplasms,
pubmed-meshheading:15540922-Carmustine,
pubmed-meshheading:15540922-Cell Culture Techniques,
pubmed-meshheading:15540922-Cell Line, Tumor,
pubmed-meshheading:15540922-Drug Resistance, Neoplasm,
pubmed-meshheading:15540922-Gliosarcoma,
pubmed-meshheading:15540922-Male,
pubmed-meshheading:15540922-Neoplasm Invasiveness,
pubmed-meshheading:15540922-Neoplasm Recurrence, Local,
pubmed-meshheading:15540922-Phenotype,
pubmed-meshheading:15540922-Rats,
pubmed-meshheading:15540922-Rats, Inbred F344
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pubmed:year |
2004
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pubmed:articleTitle |
Invasive phenotype observed in 1,3-bis(2-chloroethyl)-1-nitrosourea-resistant sublines of 9L rat glioma cells: a tumor model mimicking a recurrent malignant glioma.
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pubmed:affiliation |
Department of Neurological Surgery, Brain Tumor Research Center, University of California, San Francisco, California 94103, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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