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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2005-1-25
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pubmed:abstractText |
Insulin resistance and hyperinsulinaemia are well-recognized characteristics of anovulatory women with polycystic ovary syndrome (PCOS) but, paradoxically, steroidogenesis by PCOS granulosa cells remains responsive to insulin. The hypothesis to be tested in this study is that insulin resistance in the ovary is confined to the metabolic effects of insulin (i.e. glucose uptake and metabolism), whereas the steroidogenic action of insulin remains intact.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0268-1161
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
373-81
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:15539436-Adult,
pubmed-meshheading:15539436-Anovulation,
pubmed-meshheading:15539436-Female,
pubmed-meshheading:15539436-Follicle Stimulating Hormone,
pubmed-meshheading:15539436-Glucose,
pubmed-meshheading:15539436-Humans,
pubmed-meshheading:15539436-Hypoglycemic Agents,
pubmed-meshheading:15539436-Insulin,
pubmed-meshheading:15539436-Insulin Resistance,
pubmed-meshheading:15539436-Lactic Acid,
pubmed-meshheading:15539436-Luteal Cells,
pubmed-meshheading:15539436-Luteinizing Hormone,
pubmed-meshheading:15539436-Ovulation Induction,
pubmed-meshheading:15539436-Polycystic Ovary Syndrome,
pubmed-meshheading:15539436-Progesterone
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pubmed:year |
2005
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pubmed:articleTitle |
Impaired insulin-dependent glucose metabolism in granulosa-lutein cells from anovulatory women with polycystic ovaries.
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pubmed:affiliation |
Institute of Reproductive and Developmental Biology, Department of Obstetrics and Gynaecology, Imperial College London, London.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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