rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
7
|
pubmed:dateCreated |
2004-11-2
|
pubmed:abstractText |
The liver suffers from ischemia/reperfusion injury during transplantation. Reactive oxygen species generated by xanthine oxidase during reperfusion of the ischemic liver may be partially responsible for the hepatic injury. Oxygen free radicals are removed by antioxidant enzymes such as superoxide dismutase (SOD), catalase, and glutathione peroxidase. Using glutaraldehyde and lysine we constructed crosslinked hemoglobin, containing SOD and catalase, and assessed its ability to protect against ischemia/reperfusion injury during transplantation.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0041-1345
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
36
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1959-61
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15518711-Animals,
pubmed-meshheading:15518711-Blood Substitutes,
pubmed-meshheading:15518711-Catalase,
pubmed-meshheading:15518711-Free Radicals,
pubmed-meshheading:15518711-Hemoglobins,
pubmed-meshheading:15518711-Ischemia,
pubmed-meshheading:15518711-Liver,
pubmed-meshheading:15518711-Liver Function Tests,
pubmed-meshheading:15518711-Male,
pubmed-meshheading:15518711-Rats,
pubmed-meshheading:15518711-Rats, Sprague-Dawley,
pubmed-meshheading:15518711-Reperfusion Injury,
pubmed-meshheading:15518711-Superoxide Dismutase
|
pubmed:year |
2004
|
pubmed:articleTitle |
Effect of artificial cells on hepatic function after ischemia-reperfusion injury in liver.
|
pubmed:affiliation |
Institute for Medical Science and Chronic Disease Research Center, Keimyung University School of Medicine, Daegu, Korea.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|