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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1992-4-30
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pubmed:abstractText |
Patients with Candida colonization and invasion were studied in 20 duodenal ulcer (DU) patients, 10 non-ulcer dyspepsia (NUD) cases and 10 controls with non-gastroenterological disorders. Of 20 DU patients, Candida albicans was cultured from duodenal aspirates of 6 (30%) DU patients and pseudohyphae, indicating invasive form, were present in two (10%) prior to treatment. NUD patients and controls had positive Candida culture in 3 (30%) and 1 (10%) cases respectively; pseudohyphae were found in none. Six DU patients (30%) failed to heal with 4 weeks of cimetidine therapy; all six showed invasion of duodenal ulcer mucosa with Candida on histology. The pseudohyphae form of Candida was always found to be associated with non-healing of DU. Candidal invasion is associated with failure to respond to, H2-receptor antagonist therapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0254-8860
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
21-2
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1551708-Candidiasis,
pubmed-meshheading:1551708-Cimetidine,
pubmed-meshheading:1551708-Colony Count, Microbial,
pubmed-meshheading:1551708-Duodenal Diseases,
pubmed-meshheading:1551708-Duodenal Ulcer,
pubmed-meshheading:1551708-Dyspepsia,
pubmed-meshheading:1551708-Female,
pubmed-meshheading:1551708-Humans,
pubmed-meshheading:1551708-Male
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pubmed:year |
1992
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pubmed:articleTitle |
Cimetidine therapy and duodenal candidiasis: role in healing process.
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pubmed:affiliation |
Department of Medical Microbiology, Post Graduate Institute of Medical Education and Research, Chandigarh.
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pubmed:publicationType |
Journal Article
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