Linked Life Data

15516884

Source:http://linkedlifedata.com/resource/pubmed/id/15516884

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2004-11-1
pubmed:abstractText
Preemptive analgesia is currently in use in the management of postoperative pain and no more under search. The administration of ketamine as intraoperative analgesic agent is well-known since a long time; the analgesic properties of this drug are related to its actions as a non-competitive N-methyl-D-aspartate receptors antagonist; these receptors present an excitatory function on pain transmission and this binding seems to prevent or reverse the central sensitisation of every kind of pain, including postoperative pain. In literature, the use of this anesthetic for the preemptive analgesia in the management of postoperative pain is controversial; for this reason the aim of our study was the clinical evaluation of preemptive perioperative analgesia with low-doses ketamine.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0375-9393
pubmed:author
pubmed:issnType
Print
pubmed:volume
70
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
727-34; 734-8
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Preemptive ketamine during general anesthesia for postoperative analgesia in patients undergoing laparoscopic cholecystectomy.
pubmed:affiliation
Section of Anesthesia and Intensive Care, Department of Surgery, Anesthesia and Transplants (DISCAT), School of Anesthesia and Intensive Care, University of Genoa, Genoa, Italy.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial