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rdf:type |
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|
lifeskim:mentions |
|
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pubmed:issue |
2
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pubmed:dateCreated |
2004-11-1
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|
pubmed:abstractText |
Although beta-adrenergic blocking agents are not always considered anti-arrhythmic drugs, the results of several recent trials have suggested an anti-arrhythmic mechanism for at least part of their mortality benefit in the treatment of chronic congestive heart failure. We review background experimental and clinical evidence for the anti-arrhythmic actions of beta-blockers and then review the results of published beta-blocker heart failure trials. A majority of trials showed improvement in overall survival as well as reduction in sudden death and ventricular arrhythmias with beta-blocker treatment. Although different effects were seen with different specific agents, these trials overall support a clinically significant anti-arrhythmic effect of several beta-blockers.
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pubmed:language |
eng
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|
pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Apr
|
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pubmed:issn |
1382-4147
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
139-47
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:15516862-Adrenergic beta-Antagonists,
pubmed-meshheading:15516862-Anti-Arrhythmia Agents,
pubmed-meshheading:15516862-Arrhythmias, Cardiac,
pubmed-meshheading:15516862-Carbazoles,
pubmed-meshheading:15516862-Heart Failure,
pubmed-meshheading:15516862-Humans,
pubmed-meshheading:15516862-Metoprolol,
pubmed-meshheading:15516862-Propanolamines,
pubmed-meshheading:15516862-Randomized Controlled Trials as Topic,
pubmed-meshheading:15516862-United States
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|
pubmed:year |
2004
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|
pubmed:articleTitle |
Beta blockers as anti-arrhythmic agents.
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|
pubmed:affiliation |
Section of Cardiac Electrophysiology, Henry Ford Heart and Vascular Institute, Detroit, MI 48202, USA.
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pubmed:publicationType |
Journal Article,
Review
|
