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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2004-10-29
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pubmed:abstractText |
Histamine is a major chemical mediator in the development of nasal allergy, which is characterized by nasal hypersensitivity. In this study, we used rats sensitized by exposure to toluene diisocyanate (TDI) as an animal model of nasal hypersensitivity and examined changes in expression of histamine H1 receptor (H1R) in the nasal mucosa. The effect of glucocorticoid on upregulation of H1R in nasal mucosa induced by TDI was also examined.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0001-6489
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
124
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1053-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15513549-Animals,
pubmed-meshheading:15513549-Anti-Inflammatory Agents,
pubmed-meshheading:15513549-Dexamethasone,
pubmed-meshheading:15513549-Disease Models, Animal,
pubmed-meshheading:15513549-Glucocorticoids,
pubmed-meshheading:15513549-Male,
pubmed-meshheading:15513549-Nasal Mucosa,
pubmed-meshheading:15513549-Random Allocation,
pubmed-meshheading:15513549-Rats,
pubmed-meshheading:15513549-Receptors, Histamine H1,
pubmed-meshheading:15513549-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:15513549-Toluene 2,4-Diisocyanate,
pubmed-meshheading:15513549-Up-Regulation
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pubmed:year |
2004
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pubmed:articleTitle |
Effect of glucocorticoid on upregulation of histamine H1 receptor mRNA in nasal mucosa of rats sensitized by exposure to toluene diisocyanate.
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pubmed:affiliation |
Department of Otolaryngology, University of Tokushima School of Medicine, Tokushima, Japan. kitamura@clin.med.tokushima-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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