Source:http://linkedlifedata.com/resource/pubmed/id/15482936
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
22
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pubmed:dateCreated |
2004-10-14
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pubmed:abstractText |
A new diarylbutane lignan, 2'-hydroxy dihydroguaiaretic acid (4), and a known 8-O-4'-type neolignan, machilin D (5), were isolated from the ethyl acetate extracts of the underground parts of Saururus chinensis. Compounds 4 and 5 exhibited low-density lipoprotein (LDL)-antioxidant activity in the thiobarbituric acid-reactive substances (TBARS) assay (4: IC(50)=3.3 microM and 5: IC(50)=3.8 microM), the lag time of conjugated diene production, the relative electrophoretic mobility (REM) of ox-LDL, the apoB-100 fragmentation on copper-mediated LDL oxidation and the macrophage-mediated LDL oxidation, and radical DPPH scavenging activity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0960-894X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5623-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15482936-Antioxidants,
pubmed-meshheading:15482936-Cell Survival,
pubmed-meshheading:15482936-Humans,
pubmed-meshheading:15482936-Lignans,
pubmed-meshheading:15482936-Lipoproteins, LDL,
pubmed-meshheading:15482936-Macrophages,
pubmed-meshheading:15482936-Molecular Conformation,
pubmed-meshheading:15482936-Saururaceae,
pubmed-meshheading:15482936-Time Factors
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pubmed:year |
2004
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pubmed:articleTitle |
Antioxidant activities of a new lignan and a neolignan from Saururus chinensis.
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pubmed:affiliation |
National Research Laboratory of Lipid Metabolism & Atherosclerosis, Korea Research Institute of Bioscience and Biotechnology, 52 Oun, Yusong, Daejeon 305-333, Republic of Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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