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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2004-10-18
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pubmed:abstractText |
Defective angiogenesis, resulting in tissue ischemia, is particularly prominent in the diffuse form of systemic sclerosis (SSc). The present study was undertaken to identify possible differences between normal and SSc microvascular endothelial cells (MVECs) in the expression of the cell-associated urokinase-type plasminogen activator (uPA)/uPA receptor (uPAR) system, which is critical in the angiogenic process.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0004-3591
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pubmed:author |
pubmed-author:AnnunziatoFrancescoF,
pubmed-author:CinelliMarinaM,
pubmed-author:CosmiLorenzoL,
pubmed-author:D'AlessioSilviaS,
pubmed-author:Del RossoAngelaA,
pubmed-author:Del RossoMarioM,
pubmed-author:FanPanshengP,
pubmed-author:GuiducciSerenaS,
pubmed-author:KahalehBasharB,
pubmed-author:LiottaFrancescoF,
pubmed-author:MORELLHH,
pubmed-author:MargheriFrancescaF,
pubmed-author:Matucci-CerinicMarcoM,
pubmed-author:PucciMarcoM,
pubmed-author:SerratìSimonaS
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pubmed:copyrightInfo |
Copyright 2004 American College of Rheumatology
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pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3275-85
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15476218-Blotting, Western,
pubmed-meshheading:15476218-Endothelial Cells,
pubmed-meshheading:15476218-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:15476218-Flow Cytometry,
pubmed-meshheading:15476218-Humans,
pubmed-meshheading:15476218-Matrix Metalloproteinase 12,
pubmed-meshheading:15476218-Metalloendopeptidases,
pubmed-meshheading:15476218-Microcirculation,
pubmed-meshheading:15476218-Neovascularization, Physiologic,
pubmed-meshheading:15476218-Receptors, Cell Surface,
pubmed-meshheading:15476218-Receptors, Urokinase Plasminogen Activator,
pubmed-meshheading:15476218-Scleroderma, Systemic
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pubmed:year |
2004
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pubmed:articleTitle |
Matrix metalloproteinase 12-dependent cleavage of urokinase receptor in systemic sclerosis microvascular endothelial cells results in impaired angiogenesis.
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pubmed:affiliation |
University of Florence, Florence, Italy.
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pubmed:publicationType |
Journal Article,
In Vitro
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