Source:http://linkedlifedata.com/resource/pubmed/id/15465298
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
2004-10-6
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pubmed:abstractText |
Small-angle neutron scattering on extruded unilamellar vesicles in water was used to study bilayer thickness when cholesterol (CHOL) was added at 44.4 mol% to 1,2-dimyristoleoylphosphatidylcholine (diC14:1PC) and 1,2-dierucoylphosphatidylcholine (diC22:1PC) bilayers. Using the (1)H(2)O/(2)H(2)O contrast variation and the small-angle form of Kratky-Porod approximation, the bilayer gyration radii at infinite contrast R(g,infinity) and the bilayer thickness parameters d(g,infinity) = 12(0.5)R(g,infinity) were obtained at 30 degrees C. Addition of cholesterol to diC14:1PC increased the d(g,infinity) from 3.72 +/- 0.02 to 4.26 +/- 0.01 nm, while in the diC22:1PC bilayers the d(g,infinity) change observed was within the experimental error: +0.23 +/- 0.23 nm.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Dimyristoylphosphatidylcholine,
http://linkedlifedata.com/resource/pubmed/chemical/Lipid Bilayers,
http://linkedlifedata.com/resource/pubmed/chemical/Macromolecular Substances,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylcholines,
http://linkedlifedata.com/resource/pubmed/chemical/Water
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0927-7765
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
10
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
11-4
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pubmed:dateRevised |
2009-10-16
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pubmed:meshHeading |
pubmed-meshheading:15465298-Cholesterol,
pubmed-meshheading:15465298-Dimyristoylphosphatidylcholine,
pubmed-meshheading:15465298-Lipid Bilayers,
pubmed-meshheading:15465298-Macromolecular Substances,
pubmed-meshheading:15465298-Models, Chemical,
pubmed-meshheading:15465298-Neutron Diffraction,
pubmed-meshheading:15465298-Phosphatidylcholines,
pubmed-meshheading:15465298-Surface Properties,
pubmed-meshheading:15465298-Water
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pubmed:year |
2004
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pubmed:articleTitle |
Bilayer thickness in unilamellar extruded 1,2-dimyristoleoyl and 1,2-dierucoyl phosphatidylcholine vesicles: SANS contrast variation study of cholesterol effect.
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pubmed:affiliation |
Faculty of Pharmacy, Comenius University, Odbojárov 10, 83232 Bratislava, Slovakia. gallova@fpharm.uniba.sk
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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