Source:http://linkedlifedata.com/resource/pubmed/id/15389903
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2004-9-29
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pubmed:abstractText |
Patients with unstable angina pectoris and acute myocardial infarction have higher than normal D-dimer levels. The aim of the study was to determine the value of the D-dimer test in patients with unstable angina pectoris and a normal electrocardiogram on presentation at the emergency department. The study sample included 81 patients who met these criteria. Blood samples collected at admission were subjected to ELISA D-dimer. Findings were correlated with coronary risk factors, use of cardiac medications, blood levels of acute phase reactants (fibrinogen and C-reactive protein), cardiac enzymes levels, length of hospital stay, and catheterization findings. ELISA D-dimer levels were statistically significantly correlated with cardiac risk factors, namely male sex, older age, smoking, and hypertension (r = 0.25, P = 0.02; r = 0.43, P = 0.0001; r = 0.26, P = 0.03; r = 0.35, P = 0.002, respectively), in addition to use of cardiac medications (beta blockers, aspirin, nitrates), levels of acute phase reactants, length of stay, and catheterization findings. On multivariate analysis, only D-dimer level, age, and sex were predictors of length of stay (P = 0.018). The study suggests that D-dimer levels at admission to the emergency department may serve as an additional tool to predict the magnitude of unstable angina pectoris in patients with a normal electrocardiogram.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0361-8609
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2004 Wiley-Liss, Inc.
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pubmed:issnType |
Print
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pubmed:volume |
77
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
147-50
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:15389903-Aged,
pubmed-meshheading:15389903-Angina, Unstable,
pubmed-meshheading:15389903-Biological Markers,
pubmed-meshheading:15389903-Electrocardiography,
pubmed-meshheading:15389903-Emergency Service, Hospital,
pubmed-meshheading:15389903-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:15389903-Female,
pubmed-meshheading:15389903-Fibrin Fibrinogen Degradation Products,
pubmed-meshheading:15389903-Humans,
pubmed-meshheading:15389903-Male,
pubmed-meshheading:15389903-Middle Aged,
pubmed-meshheading:15389903-Predictive Value of Tests,
pubmed-meshheading:15389903-Prospective Studies,
pubmed-meshheading:15389903-Risk Factors
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pubmed:year |
2004
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pubmed:articleTitle |
Role of ELISA D-dimer test in patients with unstable angina pectoris presenting at the emergency department with a normal electrocardiogram.
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pubmed:affiliation |
Pulmonary Institute, Rabin Medical Center, Petah Tiqwa, Israel. davariel@zahav.net.il
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pubmed:publicationType |
Journal Article
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