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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2004-9-21
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pubmed:abstractText |
The inducement of Th1 cell-mediated immune response, possibly brought about through bacterial stimulation, may serve to control atopic disorders such as atopic dermatitis (AD). The streptococcal preparation, OK-432, has been shown a potent Th1 inducer through the action of IL-12. NC/Nga mice under ordinary conditions have been found to contract dermatitis similar to human AD.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD80,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD86,
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Ccl17 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Cd86 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL17,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokines, CC,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-12,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-12 Subunit p40,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-4,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Picibanil,
http://linkedlifedata.com/resource/pubmed/chemical/Protein Subunits,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/STAT4 Transcription Factor,
http://linkedlifedata.com/resource/pubmed/chemical/STAT6 Transcription Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Stat4 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Stat6 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Trans-Activators
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0923-1811
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2004 Japanese Society for Investigative Dermatology
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pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
187-97
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:15381240-Animals,
pubmed-meshheading:15381240-Antigens, CD,
pubmed-meshheading:15381240-Antigens, CD80,
pubmed-meshheading:15381240-Antigens, CD86,
pubmed-meshheading:15381240-Antineoplastic Agents,
pubmed-meshheading:15381240-Chemokine CCL17,
pubmed-meshheading:15381240-Chemokines, CC,
pubmed-meshheading:15381240-DNA-Binding Proteins,
pubmed-meshheading:15381240-Dermatitis, Atopic,
pubmed-meshheading:15381240-Interleukin-12,
pubmed-meshheading:15381240-Interleukin-12 Subunit p40,
pubmed-meshheading:15381240-Interleukin-4,
pubmed-meshheading:15381240-Male,
pubmed-meshheading:15381240-Membrane Glycoproteins,
pubmed-meshheading:15381240-Mice,
pubmed-meshheading:15381240-Mice, Inbred Strains,
pubmed-meshheading:15381240-Picibanil,
pubmed-meshheading:15381240-Protein Subunits,
pubmed-meshheading:15381240-RNA, Messenger,
pubmed-meshheading:15381240-STAT4 Transcription Factor,
pubmed-meshheading:15381240-STAT6 Transcription Factor,
pubmed-meshheading:15381240-Skin,
pubmed-meshheading:15381240-Th1 Cells,
pubmed-meshheading:15381240-Th2 Cells,
pubmed-meshheading:15381240-Trans-Activators
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pubmed:year |
2004
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pubmed:articleTitle |
Therapeutic effects of streptococcal preparation OK-432 on atopic dermatitis-like lesions in NC/Nga mice: possible shift from a Th2- to Th1-predominance.
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pubmed:affiliation |
Department of Dermatology, Nagaski University School of Medicine, 1-7-1 Sakamoto, Nagasaki, Japan. nu-yhori@jcom.home.ne.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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