Source:http://linkedlifedata.com/resource/pubmed/id/15374867
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2005-2-11
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pubmed:abstractText |
A promising strategy for refining genome annotations is to detect features that conflict with known functional or evolutionary relationships between groups of genes. Previous work in this area has been focused on investigating the absence of 'housekeeping' genes or components of well-studied pathways. We have sought to develop a method for improving new annotations that can automatically synthesize and use the information available in a database of other annotated genomes.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1367-4803
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
464-70
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pubmed:meshHeading |
pubmed-meshheading:15374867-Algorithms,
pubmed-meshheading:15374867-Bayes Theorem,
pubmed-meshheading:15374867-Chromosome Mapping,
pubmed-meshheading:15374867-DNA Mutational Analysis,
pubmed-meshheading:15374867-Evolution, Molecular,
pubmed-meshheading:15374867-Gene Expression Profiling,
pubmed-meshheading:15374867-Genomics,
pubmed-meshheading:15374867-Models, Genetic,
pubmed-meshheading:15374867-Models, Statistical,
pubmed-meshheading:15374867-Phylogeny,
pubmed-meshheading:15374867-Sequence Alignment,
pubmed-meshheading:15374867-Sequence Analysis, DNA
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pubmed:year |
2005
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pubmed:articleTitle |
Improving genome annotations using phylogenetic profile anomaly detection.
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pubmed:affiliation |
The Eli & Edythe L. Broad Institute, Massachusetts Institute of Technology and Harvard University 320 Charles Street, Cambridge, MA 02141, USA. tarjei@broad.mit.edu
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pubmed:publicationType |
Journal Article,
Evaluation Studies
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