15364815

Source:http://linkedlifedata.com/resource/pubmed/id/15364815

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0004238, umls-concept:C0013227, umls-concept:C0018792, umls-concept:C0087111, umls-concept:C0456387, umls-concept:C1510458, umls-concept:C1570597
pubmed:issue	13
pubmed:dateCreated	2004-9-28
pubmed:abstractText	Currently available antiarrhythmic drugs are only moderately effective against atrial fibrillation (AF) and may cause ventricular proarrhythmia. AVE0118 is a blocker of atrium-specific early K+ currents (I(Kur)/I(to)).
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0147763
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Anti-Arrhythmia Agents, http://linkedlifedata.com/resource/pubmed/chemical/Delayed Rectifier Potassium Channels, http://linkedlifedata.com/resource/pubmed/chemical/Phenethylamines, http://linkedlifedata.com/resource/pubmed/chemical/Potassium, http://linkedlifedata.com/resource/pubmed/chemical/Potassium Channel Blockers, http://linkedlifedata.com/resource/pubmed/chemical/Potassium Channels, Voltage-Gated, http://linkedlifedata.com/resource/pubmed/chemical/Sulfonamides, http://linkedlifedata.com/resource/pubmed/chemical/dofetilide, http://linkedlifedata.com/resource/pubmed/chemical/ibutilide
pubmed:status	MEDLINE
pubmed:month	Sep
pubmed:issn	1524-4539
pubmed:author	pubmed-author:AllessieM AMA, pubmed-author:BlaauwYY, pubmed-author:GögeleinHH, pubmed-author:SchottenUU, pubmed-author:TielemanR GRG, pubmed-author:van HunnikAA
pubmed:issnType	Electronic
pubmed:day	28
pubmed:volume	110
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1717-24
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:15364815-Action Potentials, pubmed-meshheading:15364815-Animals, pubmed-meshheading:15364815-Anti-Arrhythmia Agents, pubmed-meshheading:15364815-Atrial Fibrillation, pubmed-meshheading:15364815-Cardiac Pacing, Artificial, pubmed-meshheading:15364815-Delayed Rectifier Potassium Channels, pubmed-meshheading:15364815-Drug Evaluation, Preclinical, pubmed-meshheading:15364815-Electric Countershock, pubmed-meshheading:15364815-Female, pubmed-meshheading:15364815-Goats, pubmed-meshheading:15364815-Heart Atria, pubmed-meshheading:15364815-Heart Conduction System, pubmed-meshheading:15364815-Infusions, Intravenous, pubmed-meshheading:15364815-Ion Transport, pubmed-meshheading:15364815-Neural Conduction, pubmed-meshheading:15364815-Phenethylamines, pubmed-meshheading:15364815-Potassium, pubmed-meshheading:15364815-Potassium Channel Blockers, pubmed-meshheading:15364815-Potassium Channels, Voltage-Gated, pubmed-meshheading:15364815-Sulfonamides
pubmed:year	2004
pubmed:articleTitle	"Early" class III drugs for the treatment of atrial fibrillation: efficacy and atrial selectivity of AVE0118 in remodeled atria of the goat.
pubmed:affiliation	Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.
pubmed:publicationType	Journal Article, Comparative Study, Research Support, Non-U.S. Gov't