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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2004-9-14
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pubmed:abstractText |
To evaluate the efficacy of a novel lipopolysaccharide (LPS) antagonist, E5531, in blocking LPS-induced cardiac responses including myocardial depression (as assessed by relatively load-independent echocardiographic indices of contractility) in a human model of experimental endotoxemia.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0012-3692
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
126
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
860-7
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:15364767-Adolescent,
pubmed-meshheading:15364767-Adult,
pubmed-meshheading:15364767-Cardiac Output, Low,
pubmed-meshheading:15364767-Dose-Response Relationship, Drug,
pubmed-meshheading:15364767-Double-Blind Method,
pubmed-meshheading:15364767-Endotoxemia,
pubmed-meshheading:15364767-Escherichia coli,
pubmed-meshheading:15364767-Hemodynamics,
pubmed-meshheading:15364767-Humans,
pubmed-meshheading:15364767-Intensive Care Units,
pubmed-meshheading:15364767-Lipid A,
pubmed-meshheading:15364767-Lipopolysaccharides,
pubmed-meshheading:15364767-Male,
pubmed-meshheading:15364767-Myocardial Contraction
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pubmed:year |
2004
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pubmed:articleTitle |
Experimental human endotoxemia is associated with depression of load-independent contractility indices: prevention by the lipid a analogue E5531.
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pubmed:affiliation |
Section of Critical Care Medicine, Health Sciences Centre, GE706, 820 Sherbrook St, Winnipeg, MB, Canada, R3A 1R9. akumar61@yahoo.com
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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