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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2004-9-13
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pubmed:abstractText |
The pathogenesis of pain in pancreatitis remains poorly understood. We hypothesized that trypsin, a key inflammatory mediator in this condition, can also activate nociceptive neurons via the proteinase-activated receptor 2.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0016-5085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
127
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
883-91
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15362043-Animals,
pubmed-meshheading:15362043-Ganglia, Spinal,
pubmed-meshheading:15362043-Male,
pubmed-meshheading:15362043-Models, Animal,
pubmed-meshheading:15362043-Nociceptors,
pubmed-meshheading:15362043-Pain,
pubmed-meshheading:15362043-Pain Measurement,
pubmed-meshheading:15362043-Pancreas,
pubmed-meshheading:15362043-Pancreatitis,
pubmed-meshheading:15362043-Proto-Oncogene Proteins c-fos,
pubmed-meshheading:15362043-Rats,
pubmed-meshheading:15362043-Rats, Sprague-Dawley,
pubmed-meshheading:15362043-Receptor, PAR-2,
pubmed-meshheading:15362043-Receptors, Drug,
pubmed-meshheading:15362043-TRPV Cation Channels,
pubmed-meshheading:15362043-Trypsin
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pubmed:year |
2004
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pubmed:articleTitle |
Trypsin mediates nociception via the proteinase-activated receptor 2: a potentially novel role in pancreatic pain.
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pubmed:affiliation |
Enteric Neuromuscular Disorders and Pain Laboratory, Division of Gastroenterology and Hepatology, University of Texas Medical Branch, Galveston, Texas, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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