Source:http://linkedlifedata.com/resource/pubmed/id/15351040
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2004-9-7
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pubmed:abstractText |
Up to 28-fold differences in vacA expression in Helicobacter pylori strains grown in vitro were demonstrated by real time quantitative RT-PCR. These large differences in expression were unrelated to putative -35 and -10 motifs or to other untranslated sequences upstream of the ATG start site. The lack of correlation between promoter sequences and the vacA expression levels suggest the potential existence of a bacterial strain-specific factor, as earlier proposed by others on the basis of reporter gene fusions.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0882-4010
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
163-7
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15351040-Bacterial Proteins,
pubmed-meshheading:15351040-Base Sequence,
pubmed-meshheading:15351040-Cytotoxins,
pubmed-meshheading:15351040-Gene Expression Regulation, Bacterial,
pubmed-meshheading:15351040-Helicobacter pylori,
pubmed-meshheading:15351040-Humans,
pubmed-meshheading:15351040-Molecular Sequence Data,
pubmed-meshheading:15351040-Promoter Regions, Genetic,
pubmed-meshheading:15351040-RNA, Messenger,
pubmed-meshheading:15351040-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:15351040-Transcription, Genetic
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pubmed:year |
2004
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pubmed:articleTitle |
Quantitation of H. pylori cytotoxin mRNA by real-time RT-PCR shows a wide expression range that does not correlate with promoter sequences.
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pubmed:affiliation |
Centro de Investigaciones sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública, Av. Universidad 655 Cuernavaca, Mor. C. P. 62508, Mexico. gayala@correo.insp.mx
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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