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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1992-7-10
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pubmed:abstractText |
We report on 9 infants with severe combined immunodeficiency (SCID), who additionally showed signs of Omenn syndrome with an exfoliative dermatopathy, alopecia, enlarged lymph nodes, a hepatomegalia and a striking blood eosinophilia. The immunological evaluation revealed the characteristic abnormalities of SCID with cellular and humoral immunodeficiency. All patients however had the unusual finding of mature T cells in the peripheral blood. By HLA typing these cells were noted to be of maternal origin in 5 patients. In the other 4 patients the T cells were of host origin. We asked for additional differences between both patient groups.
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pubmed:language |
ger
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0026-9298
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
140
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
188-93
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1534868-Bone Marrow,
pubmed-meshheading:1534868-Bone Marrow Transplantation,
pubmed-meshheading:1534868-Dermatitis, Exfoliative,
pubmed-meshheading:1534868-Eosinophilia,
pubmed-meshheading:1534868-Female,
pubmed-meshheading:1534868-Fetomaternal Transfusion,
pubmed-meshheading:1534868-HLA Antigens,
pubmed-meshheading:1534868-Haplotypes,
pubmed-meshheading:1534868-Humans,
pubmed-meshheading:1534868-Immunoblastic Lymphadenopathy,
pubmed-meshheading:1534868-Immunoglobulins,
pubmed-meshheading:1534868-Infant,
pubmed-meshheading:1534868-Infant, Newborn,
pubmed-meshheading:1534868-Lymph Nodes,
pubmed-meshheading:1534868-Male,
pubmed-meshheading:1534868-Pregnancy,
pubmed-meshheading:1534868-Severe Combined Immunodeficiency,
pubmed-meshheading:1534868-Syndrome,
pubmed-meshheading:1534868-T-Lymphocytes
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pubmed:year |
1992
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pubmed:articleTitle |
[Severe combined immune defect. Presentation of exfoliative dermatitis with eosinophilia and lymphadenopathy].
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pubmed:affiliation |
Abteilung Pädiatrie II, Universität Ulm.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
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