Linked Life Data

15342438

Source:http://linkedlifedata.com/resource/pubmed/id/15342438

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2005-4-22
pubmed:abstractText
Electrophysiological studies have revealed a pre-attentive change-detection system in the auditory modality. This system emits a signal termed the mismatch negativity (MMN) when any detectable change in a regular pattern of auditory stimulation occurs. The precise intracranial sources underlying MMN generation, and in particular whether these vary as a function of the acoustic feature that changes, is a matter of some debate. Using functional magnetic resonance imaging, we show that anatomically distinct networks of auditory cortices are activated as a function of the deviating acoustic feature--in this case, tone frequency and tone duration--strongly supporting the hypothesis that MMN generators in auditory cortex are feature dependent. We also detail regions of the frontal and parietal cortices activated by change-detection processes. These regions also show feature dependence and we hypothesize that they reflect recruitment of attention-switching mechanisms.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1047-3211
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
545-51
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
The neural circuitry of pre-attentive auditory change-detection: an fMRI study of pitch and duration mismatch negativity generators.
pubmed:affiliation
The Cognitive Neurophysiology Laboratory, Program in Cognitive Neuroscience and Schizophrenia, Nathan Kline Institute for Psychiatric Research, 140 Old Orangeburg Road, Orangeburg, NY 10962, USA. molholm@nki.rfmh.org
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S.