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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2004-9-1
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pubmed:abstractText |
Studies in isolated cardiac myocytes have demonstrated that signaling via specific beta1-adrenergic receptor subtypes (beta1ARs) promotes but that signaling via beta2ARs protects from cell death. We hypothesized that prolonged beta(2)AR stimulation or beta1AR blockade would each protect myocytes from death and thereby ameliorate cardiac remodeling in chronic heart failure.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1524-4539
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
31
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pubmed:volume |
110
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1083-90
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:15313944-Adrenergic beta-1 Receptor Antagonists,
pubmed-meshheading:15313944-Adrenergic beta-2 Receptor Agonists,
pubmed-meshheading:15313944-Adrenergic beta-Agonists,
pubmed-meshheading:15313944-Adrenergic beta-Antagonists,
pubmed-meshheading:15313944-Animals,
pubmed-meshheading:15313944-Apoptosis,
pubmed-meshheading:15313944-Cardiomyopathy, Dilated,
pubmed-meshheading:15313944-Cell Size,
pubmed-meshheading:15313944-Ethanolamines,
pubmed-meshheading:15313944-Fenoterol,
pubmed-meshheading:15313944-Male,
pubmed-meshheading:15313944-Metoprolol,
pubmed-meshheading:15313944-Myocardial Infarction,
pubmed-meshheading:15313944-Myocardium,
pubmed-meshheading:15313944-Myocytes, Cardiac,
pubmed-meshheading:15313944-Organ Size,
pubmed-meshheading:15313944-Rats,
pubmed-meshheading:15313944-Rats, Wistar,
pubmed-meshheading:15313944-Signal Transduction,
pubmed-meshheading:15313944-Ventricular Function, Left
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pubmed:year |
2004
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pubmed:articleTitle |
Beneficial effects of chronic pharmacological manipulation of beta-adrenoreceptor subtype signaling in rodent dilated ischemic cardiomyopathy.
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pubmed:affiliation |
Gerontology Research Center, Baltimore, MD 21224, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study
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