Source:http://linkedlifedata.com/resource/pubmed/id/15304598
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
2004-8-12
|
| pubmed:abstractText |
In this postlicensing surveillance study in a large unselected population, data were collected prospectively on all patients prescribed levetiracetam (LEV) at a regional epilepsy clinic over a 2-year period. Two hundred forty-five (69.2%) patients remained on LEV, with 8.8% achieving remission and some improvement in seizure control in 49.3%. Sedation was the most common adverse effect (10.7%), but mood disturbance was more likely to lead to discontinuation (4.8%). Cumulative probability of remaining on LEV at 12 months was 0.74 (95% CI 0.69 to 0.79). Factors predictive of a poorer retention were a greater number of previous antiepileptic drugs and a faster initial titration regimen.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
1526-632X
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:day |
10
|
| pubmed:volume |
63
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
568-70
|
| pubmed:meshHeading |
pubmed-meshheading:15304598-Anticonvulsants,
pubmed-meshheading:15304598-Consciousness Disorders,
pubmed-meshheading:15304598-Drug Administration Schedule,
pubmed-meshheading:15304598-Drug Resistance,
pubmed-meshheading:15304598-Drug Therapy, Combination,
pubmed-meshheading:15304598-Epilepsy,
pubmed-meshheading:15304598-Female,
pubmed-meshheading:15304598-Follow-Up Studies,
pubmed-meshheading:15304598-Humans,
pubmed-meshheading:15304598-Life Tables,
pubmed-meshheading:15304598-Male,
pubmed-meshheading:15304598-Mood Disorders,
pubmed-meshheading:15304598-Patient Dropouts,
pubmed-meshheading:15304598-Piracetam,
pubmed-meshheading:15304598-Product Surveillance, Postmarketing,
pubmed-meshheading:15304598-Prospective Studies,
pubmed-meshheading:15304598-Remission Induction,
pubmed-meshheading:15304598-Treatment Outcome
|
| pubmed:year |
2004
|
| pubmed:articleTitle |
A prospective analysis of the outcome of levetiracetam in clinical practice.
|
| pubmed:affiliation |
Department of Neurology, Hope Hospital, Stott Lane, Salford M6 8HD, UK. andrew@nicolson71.freeserve.co.uk
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Multicenter Study,
Clinical Trial, Phase IV
|