Linked Life Data

15303836

Source:http://linkedlifedata.com/resource/pubmed/id/15303836

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
32
pubmed:dateCreated
2004-8-12
pubmed:abstractText
While many parallel synthesis methods developed by the pharmaceutical and life science communities are being applied to polymer synthesis, there remains a need to construct "libraries" of polymeric materials that explore a wider range of polymer structures with accuracy, flexibility, and rapid, often small, changes. We report the use of microfluidics to create an environment for continuous controlled radical polymerization. Varying either the flow rate or the relative concentrations of reactants (i.e., stoichiometry) controls the molecular properties of the products. Molecular variables, here molecular weight, can then be varied continuously. Well-defined materials with narrow molecular weight distributions are produced inside the microfluidic reactor and are available for processing, such as further mixing, deposition, or coating on surfaces. Preliminary kinetic data appear to agree well with literature values reported for larger-scale reactions.
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Aug
pubmed:issn
0002-7863
pubmed:author
pubmed:issnType
Print
pubmed:day
18
pubmed:volume
126
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
9880-1
pubmed:dateRevised
2008-1-17
pubmed:year
2004
pubmed:articleTitle
A new synthetic method for controlled polymerization using a microfluidic system.
pubmed:affiliation
Polymers Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA.
pubmed:publicationType
Journal Article