Source:http://linkedlifedata.com/resource/pubmed/id/15286782
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2004-8-2
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pubmed:abstractText |
The field of vaccinology began in ignorance of how protection was instilled in vaccine recipients. Today, a greater knowledge of immunology allows us to better understand what is being stimulated by various vaccines that leads to their protective effects: that is, their correlates of protection. Here we describe what is known about the correlates of protection for existing vaccines against a range of different viral diseases and discuss the correlates of protection against disease during natural infection with HIV-1. We will also discuss why it is important to design phase 3 clinical trials of HIV vaccines to determine the correlates of protection for each individual vaccine.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1078-8956
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
806-10
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15286782-AIDS Vaccines,
pubmed-meshheading:15286782-Antibody Formation,
pubmed-meshheading:15286782-HIV Infections,
pubmed-meshheading:15286782-HIV-1,
pubmed-meshheading:15286782-Humans,
pubmed-meshheading:15286782-Immunity, Cellular,
pubmed-meshheading:15286782-Monitoring, Immunologic,
pubmed-meshheading:15286782-Virus Diseases
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pubmed:year |
2004
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pubmed:articleTitle |
Correlates of immune protection in HIV-1 infection: what we know, what we don't know, what we should know.
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pubmed:affiliation |
Laboratory of AIDS Immunopathogenesis, Division of Immunology and Allergy, Department of Medicine, Centre Hospitalier Universitaire Vaudois, University of Lausanne, 1011 Lausanne, Switzerland. giuseppe.pantaleo@chuv.hospvd.ch
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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