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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2004-7-20
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pubmed:abstractText |
Experimental brain damage was induced in 16 fetal sheep by umbilical cord occlusion, and the correlation of neuron-specific enolase (NSE) or S100B with the damage grade was investigated in seven fetuses. Significant correlations of damage degree with NSE (p = 0.016) and S100B (p = 0.018) in serum 2 h after insult were shown by Spearman's test. These findings suggest that they represent potentially useful markers for detecting brain damage at early stage after ischemic insult.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0006-8993
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
20
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pubmed:volume |
1018
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
136-40
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:15262215-Animals,
pubmed-meshheading:15262215-Biological Markers,
pubmed-meshheading:15262215-Brain,
pubmed-meshheading:15262215-Constriction, Pathologic,
pubmed-meshheading:15262215-Disease Models, Animal,
pubmed-meshheading:15262215-Down-Regulation,
pubmed-meshheading:15262215-Fetal Hypoxia,
pubmed-meshheading:15262215-Fetus,
pubmed-meshheading:15262215-Hypoxia, Brain,
pubmed-meshheading:15262215-Immunohistochemistry,
pubmed-meshheading:15262215-Nerve Growth Factors,
pubmed-meshheading:15262215-Neurons,
pubmed-meshheading:15262215-Observer Variation,
pubmed-meshheading:15262215-Phosphopyruvate Hydratase,
pubmed-meshheading:15262215-Predictive Value of Tests,
pubmed-meshheading:15262215-Reaction Time,
pubmed-meshheading:15262215-Reproducibility of Results,
pubmed-meshheading:15262215-S100 Proteins,
pubmed-meshheading:15262215-Sheep,
pubmed-meshheading:15262215-Umbilical Cord,
pubmed-meshheading:15262215-Up-Regulation
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pubmed:year |
2004
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pubmed:articleTitle |
Correlation of neuron-specific enolase and S100B with histological cerebral damage in fetal sheep after severe asphyxia.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, Japan. fujii-e@ncchd.go.jp
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pubmed:publicationType |
Journal Article
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