rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1979-1-26
|
pubmed:abstractText |
LPS proved to be good B-cell mitogen for fetal pig spleen cells and induced proliferation as well as differentiation of virgin resting small lymphocytes within 48 hours of cultivation. The LPS-activated lymphocytes and blast-like cells were more intensely labeled with anti-Ig antibodies than control cells, most probably due to an increased density of surface Ig. A lower percentage of LPS-activated cells was found to be labeled with F(ab)2 fragment of anti-L than with anti-L antibodies having an intact Fc fragment. The latter finding suggests non-specific binding of antisera to Fc receptors which appear to be activated on LPS-stimulated lymphoid cells.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0323-4398
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
24
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
175-82
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:152572-Animals,
pubmed-meshheading:152572-B-Lymphocytes,
pubmed-meshheading:152572-Binding Sites, Antibody,
pubmed-meshheading:152572-Fetus,
pubmed-meshheading:152572-Immunoglobulin Fab Fragments,
pubmed-meshheading:152572-Immunoglobulin Fc Fragments,
pubmed-meshheading:152572-Lipopolysaccharides,
pubmed-meshheading:152572-Lymphocyte Activation,
pubmed-meshheading:152572-Receptors, Antigen, B-Cell,
pubmed-meshheading:152572-Spleen,
pubmed-meshheading:152572-Swine
|
pubmed:year |
1978
|
pubmed:articleTitle |
Stimulation of fetal spleen cells with lipopolysaccharides.
|
pubmed:publicationType |
Journal Article
|