Source:http://linkedlifedata.com/resource/pubmed/id/15254693
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2004-7-15
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pubmed:abstractText |
This study compared prediction of the recurrence of breast cancer by detection of occult neoplastic cells (ONCs) in lymph nodes or by using the criteria for a high risk of recurrence and metastasis of gastric/large bowel cancer. The subjects were 45 patients with stage II and III node-positive breast cancer. Prediction of recurrence by detection of ONCs showed a sensitivity of 78.6% (11/14), a false-negative rate of 21.4% (3/14), a specificity of 96.4% (30/31), a false-positive rate of 3.2% (1/31), and an accuracy of 87.7% in patients with stage II and III node-positive cancer. Prediction of recurrence based on positivity for at least 2 of the high-risk criteria showed a sensitivity of 92.9% (13/14), a false-negative rate of 7.1% (1/14), a specificity of 87.1% (27/31), a false-positive rate of 12.9% (4/31), and an accuracy of 90.0% in patients with stage II and III node-positive cancer. These results suggest that ONCs plus the high-risk criteria are useful for predicting recurrence/metastasis of stage II and III node-positive breast cancer during the early postoperative period with a high sensitivity and accuracy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1021-335X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
303-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15254693-Breast Neoplasms,
pubmed-meshheading:15254693-Female,
pubmed-meshheading:15254693-Humans,
pubmed-meshheading:15254693-Immunohistochemistry,
pubmed-meshheading:15254693-Keratins,
pubmed-meshheading:15254693-Lymph Nodes,
pubmed-meshheading:15254693-Lymphatic Metastasis,
pubmed-meshheading:15254693-Neoplasm Metastasis,
pubmed-meshheading:15254693-Recurrence,
pubmed-meshheading:15254693-Sensitivity and Specificity,
pubmed-meshheading:15254693-Time Factors
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pubmed:year |
2004
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pubmed:articleTitle |
Predicting the recurrence/metastasis of stage II and III breast cancer with lymph node metastasis.
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pubmed:affiliation |
Department of Surgery, Tokai University Oiso Hospital, Oiso, Kanagawa 259-0198, Japan. onc-res@oiso.u-tokai.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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