Linked Life Data

15248081

Source:http://linkedlifedata.com/resource/pubmed/id/15248081

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2005-3-31
pubmed:abstractText
The aim of this study was to investigate the efficacy of bipolar radiofrequency ablation (RFA) with the open-perfused electrode and cooled-wet electrode. Bipolar RF was applied for 20 min to the ex vivo bovine liver using either the Berchtold system with two 16-gauge open-perfused electrodes (group A, n=15) or the Radionics system with two 15-gauge cooled-wet electrodes (group B, n=15). In both groups, two electrodes were placed 3 cm apart. The ablation zone was created by the RF energy delivered together with the infusion of 5% hypertonic saline (2 ml/min). The dimension of the ablation zone, its shape and the changes in the impedance and W s of two groups during the RFA were examined and documented. The vertical diameter (Dv) along the probe, the long-axis diameter (Dl) perpendicular to the Dv in the longitudinal plane and the short-axis diameter of the ablation zone (Ds) in the transverse plane through the midpoint between the tips of two probes were measured. The mean accumulated energy output in the Radionics system was higher than in the Berchtold system (159,887.0+/-36,423 W s vs. 87,555.1+/-86,787 W s). The difference was statistically significant (P<0.05). In group A, the impedance intermittently rose to above 700 Omega during the RFA in all sessions, which led to a gradual decrease of the power output to lower than 30 W. In group B, on the other hand, the impedance did not change markedly. The mean Dv value of the coagulation necrosis in group B was significantly longer than in group A (5.0+/-0.4 cm vs. 4.3+/-0.6 cm, P<0.05). The mean Dl and Ds were 6.7+/-0.5 cm and 5.0+/-0.8 cm in group A, and 6.5+/-0.8 cm and 5.5+/-0.7 cm in group B, respectively (P>0.05). The data demonstrate that the cooled-wet electrode generates the more spherical ablation zone than the open-perfused electrode. With approximately doubled power output, the bipolar RFA with the cooled-wet electrodes induces a larger volume of tissue coagulation than with the open-perfused electrodes.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0938-7994
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
759-64
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Bipolar radiofrequency ablation in ex vivo bovine liver with the open-perfused system versus the cooled-wet system.
pubmed:affiliation
Department of Diagnostic Radiology, Clinical Research Institute, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, Seoul, 110-744, South Korea. leejm@radcom.snu.ac.kr
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't