rdf:type |
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lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
2004-7-12
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pubmed:abstractText |
To report our development of a new application of the inter-Alu long polymerase chain reaction (PCR) for genomic scanning to screen for tumor-specific alterations in tumor DNA. Using this method, we detected a rearranged chromosomal region in renal cell carcinomas (RCCs). We then examined tumor-specific allelic loss in this region using microsatellite markers and determined whether a relationship was present between this allelic loss and the clinicopathologic features of the patients.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
|
pubmed:issn |
1527-9995
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pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
64
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
176-81
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15245966-Adult,
pubmed-meshheading:15245966-Aged,
pubmed-meshheading:15245966-Aged, 80 and over,
pubmed-meshheading:15245966-Alu Elements,
pubmed-meshheading:15245966-Carcinoma, Renal Cell,
pubmed-meshheading:15245966-Chromosomes, Human, Pair 14,
pubmed-meshheading:15245966-Disease Progression,
pubmed-meshheading:15245966-Expressed Sequence Tags,
pubmed-meshheading:15245966-Female,
pubmed-meshheading:15245966-Follow-Up Studies,
pubmed-meshheading:15245966-Genes, Tumor Suppressor,
pubmed-meshheading:15245966-Humans,
pubmed-meshheading:15245966-Kidney Neoplasms,
pubmed-meshheading:15245966-Life Tables,
pubmed-meshheading:15245966-Loss of Heterozygosity,
pubmed-meshheading:15245966-Male,
pubmed-meshheading:15245966-Microsatellite Repeats,
pubmed-meshheading:15245966-Middle Aged,
pubmed-meshheading:15245966-Polymerase Chain Reaction,
pubmed-meshheading:15245966-Polymorphism, Single-Stranded Conformational,
pubmed-meshheading:15245966-Prognosis,
pubmed-meshheading:15245966-Radiation Hybrid Mapping,
pubmed-meshheading:15245966-Survival Analysis
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pubmed:year |
2004
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pubmed:articleTitle |
Positive correlation between allelic loss at chromosome 14q24-31 and poor prognosis of patients with renal cell carcinoma.
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pubmed:affiliation |
Department of Molecular Genetics, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|