Source:http://linkedlifedata.com/resource/pubmed/id/15241785
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2004-7-8
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pubmed:abstractText |
Preclinical and clinical studies have demonstrated that interleukin 2 (IL-2), interleukin 12 (IL-12), and some other cytokines, play important roles in activating host immune responses against tumor growth. However, severe side effects caused by systemic high-dose administration of these cytokines limit their clinical application. In our previous study, local high doses of IL-2 were achieved by a GPI-anchoring technology; therefore, it will be interesting to know if this technology works for other cytokines.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1099-498X
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2004 John Wiley & Sons, Ltd.
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pubmed:issnType |
Print
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
777-85
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15241785-Animals,
pubmed-meshheading:15241785-Cell Division,
pubmed-meshheading:15241785-Cell Line, Tumor,
pubmed-meshheading:15241785-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:15241785-Female,
pubmed-meshheading:15241785-Glycosylphosphatidylinositols,
pubmed-meshheading:15241785-Interleukin-12,
pubmed-meshheading:15241785-Interleukin-2,
pubmed-meshheading:15241785-Lymphocytes, Tumor-Infiltrating,
pubmed-meshheading:15241785-Mice,
pubmed-meshheading:15241785-Mice, Inbred C57BL,
pubmed-meshheading:15241785-Neoplasms, Experimental
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pubmed:year |
2004
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pubmed:articleTitle |
Synergistic anti-tumor effect of glycosylphosphatidylinositol-anchored IL-2 and IL-12.
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pubmed:affiliation |
Department of Biological Sciences, Clemson University, Clemson, South Carolina, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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