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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2004-7-1
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pubmed:abstractText |
Pulmonary Langerhans cell histiocytosis (PLCH) is characterized by the presence of lesions containing numerous activated Langerhans cells (LCs). An uncontrolled immune response sustained by activated LCs seems to be involved in the pathogenesis of the disease. The aim of this study was to establish whether disruption of LC apoptosis related to the expression of the Bcl-2 family proteins is implicated in the maintenance of PLCH lesions.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0309-0167
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
20-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15228440-Adult,
pubmed-meshheading:15228440-Apoptosis,
pubmed-meshheading:15228440-Caspase 3,
pubmed-meshheading:15228440-Caspases,
pubmed-meshheading:15228440-Enzyme Activation,
pubmed-meshheading:15228440-Female,
pubmed-meshheading:15228440-Histiocytosis, Langerhans-Cell,
pubmed-meshheading:15228440-Humans,
pubmed-meshheading:15228440-Immunohistochemistry,
pubmed-meshheading:15228440-In Situ Nick-End Labeling,
pubmed-meshheading:15228440-Langerhans Cells,
pubmed-meshheading:15228440-Lung,
pubmed-meshheading:15228440-Male,
pubmed-meshheading:15228440-Middle Aged,
pubmed-meshheading:15228440-Proto-Oncogene Proteins c-bcl-2,
pubmed-meshheading:15228440-bcl-2-Associated X Protein,
pubmed-meshheading:15228440-bcl-X Protein
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pubmed:year |
2004
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pubmed:articleTitle |
Expression of apoptosis-regulatory proteins in lesions of pulmonary Langerhans cell histiocytosis.
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pubmed:affiliation |
INSERM U 408, Faculté de Médecine Xavier Bichat, Paris, France.
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pubmed:publicationType |
Journal Article
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