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rdf:type |
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lifeskim:mentions |
umls-concept:C0005740,
umls-concept:C0008059,
umls-concept:C0008838,
umls-concept:C0015133,
umls-concept:C0034656,
umls-concept:C0205653,
umls-concept:C0740345,
umls-concept:C1516476,
umls-concept:C1518578,
umls-concept:C1521725,
umls-concept:C1521750,
umls-concept:C1707455
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pubmed:issue |
13
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pubmed:dateCreated |
2004-6-30
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pubmed:abstractText |
To determine in a randomized comparison whether combination chemotherapy with high-dose cisplatin (HDPEB) improves the event-free (EFS) and overall (OS) survival of children and adolescents with high-risk malignant germ cell tumors (MGCT) as compared with standard-dose cisplatin (PEB) and to compare the regimens' toxicity.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0732-183X
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pubmed:author |
pubmed-author:AwadM AMA,
pubmed-author:BillmireDeborah FDF,
pubmed-author:CastleberryRobert PRP,
pubmed-author:Children's Cancer Group 8882,
pubmed-author:ColombaniPaulP,
pubmed-author:CullenJohn WJW,
pubmed-author:CushingBarbaraB,
pubmed-author:DavisMary MargaretMM,
pubmed-author:GillerRogerR,
pubmed-author:HawkinsEdith PEP,
pubmed-author:LauerStephen JSJ,
pubmed-author:LondonWendy BWB,
pubmed-author:MarinaNeyssa MNM,
pubmed-author:OlsonThomas ATA,
pubmed-author:PerlmanElizabeth JEJ,
pubmed-author:RescorlaFrederickF,
pubmed-author:RogersPaul CPC,
pubmed-author:VinocurCharles DCD
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2691-700
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15226336-Adolescent,
pubmed-meshheading:15226336-Antineoplastic Agents,
pubmed-meshheading:15226336-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:15226336-Bleomycin,
pubmed-meshheading:15226336-Child,
pubmed-meshheading:15226336-Child, Preschool,
pubmed-meshheading:15226336-Cisplatin,
pubmed-meshheading:15226336-Disease-Free Survival,
pubmed-meshheading:15226336-Dose-Response Relationship, Drug,
pubmed-meshheading:15226336-Etoposide,
pubmed-meshheading:15226336-Female,
pubmed-meshheading:15226336-Humans,
pubmed-meshheading:15226336-Male,
pubmed-meshheading:15226336-Neoplasms, Germ Cell and Embryonal,
pubmed-meshheading:15226336-Ovarian Neoplasms,
pubmed-meshheading:15226336-Prognosis,
pubmed-meshheading:15226336-Risk Factors,
pubmed-meshheading:15226336-Testicular Neoplasms
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pubmed:year |
2004
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pubmed:articleTitle |
Randomized comparison of combination chemotherapy with etoposide, bleomycin, and either high-dose or standard-dose cisplatin in children and adolescents with high-risk malignant germ cell tumors: a pediatric intergroup study--Pediatric Oncology Group 9049 and Children's Cancer Group 8882.
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pubmed:affiliation |
Wayne State University School of Medicine and Children's Hospital of Michigan, Detroit, MI, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Randomized Controlled Trial,
Multicenter Study
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