15225723

Source:http://linkedlifedata.com/resource/pubmed/id/15225723

Download in:

Switch to

Custom View

Named Graph Language Inference

Statements in which the resource exists as a subject.
Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0038477, umls-concept:C0205250, umls-concept:C0205549, umls-concept:C0220781, umls-concept:C1882074, umls-concept:C1883254, umls-concept:C2267054, umls-concept:C2348042, umls-concept:C2825492
pubmed:issue	15
pubmed:dateCreated	2004-6-30
pubmed:abstractText	Parallel synthesis and iterative optimization led to the discovery of a series of potent and specific factor Xa inhibitors demonstrating excellent in vitro activity with promising pharmacokinetics.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antithrombin III, http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Factor Xa
pubmed:status	MEDLINE
pubmed:month	Aug
pubmed:issn	0960-894X
pubmed:author	pubmed-author:ArfstenAnnA, pubmed-author:BauerShawn MSM, pubmed-author:GoldmanErick AEA, pubmed-author:HuangBrianB, pubmed-author:HuangWenrongW, pubmed-author:HutchaleelahaAthiwatA, pubmed-author:KothuleJayaJ, pubmed-author:LinJoyceJ, pubmed-author:MayBridgetB, pubmed-author:ScarboroughRobert MRM, pubmed-author:SinhaUmaU, pubmed-author:SuTingT, pubmed-author:WangLingyanL, pubmed-author:WongPaul WPW, pubmed-author:WoolfreyJohnJ, pubmed-author:WuYanhongY, pubmed-author:ZhuBing-YanBY, pubmed-author:ZuckettJingmei FJF
pubmed:issnType	Print
pubmed:day	2
pubmed:volume	14
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	4045-50
pubmed:meshHeading	pubmed-meshheading:15225723-Antithrombin III, pubmed-meshheading:15225723-Enzyme Inhibitors, pubmed-meshheading:15225723-Factor Xa, pubmed-meshheading:15225723-Humans, pubmed-meshheading:15225723-Molecular Conformation, pubmed-meshheading:15225723-Molecular Structure, pubmed-meshheading:15225723-Structure-Activity Relationship
pubmed:year	2004
pubmed:articleTitle	Parallel synthesis and structure-activity relationships of a series of highly potent, selective, and neutral factor Xa inhibitors.
pubmed:affiliation	Department of Medicinal Chemistry, Millennium Pharmaceuticals Inc., 256 East Grand Avenue, Suite 22, South San Francisco, CA 94080, USA. sbauer@portola.com
pubmed:publicationType	Journal Article