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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2004-6-25
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pubmed:abstractText |
Placental leucine aminopeptidase (P-LAP) is a cell surface aminopeptidase (oxytocinase). We cloned P-LAP cDNA and found a widespread tissue distribution of P-LAP. Since P-LAP can degrade several small peptide hormones such as oxytocin, this enzyme may affect many cellular functions of carcinoma cells as well as normal cells. This study investigated whether the expression of P-LAP correlates with clinicopathologic factors and prognosis in patients with endometrial endometrioid adenocarcinoma.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0030-2414
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2004 S. Karger AG, Basel
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pubmed:issnType |
Print
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
288-95
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pubmed:dateRevised |
2009-11-24
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pubmed:meshHeading |
pubmed-meshheading:15218296-Analysis of Variance,
pubmed-meshheading:15218296-Carcinoma, Endometrioid,
pubmed-meshheading:15218296-Cystinyl Aminopeptidase,
pubmed-meshheading:15218296-Disease-Free Survival,
pubmed-meshheading:15218296-Endometrial Neoplasms,
pubmed-meshheading:15218296-Female,
pubmed-meshheading:15218296-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:15218296-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:15218296-Humans,
pubmed-meshheading:15218296-Immunohistochemistry,
pubmed-meshheading:15218296-Middle Aged,
pubmed-meshheading:15218296-Predictive Value of Tests,
pubmed-meshheading:15218296-Prognosis,
pubmed-meshheading:15218296-Tumor Markers, Biological,
pubmed-meshheading:15218296-Up-Regulation
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pubmed:year |
2004
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pubmed:articleTitle |
Expression of placental leucine aminopeptidase is associated with a poor outcome in endometrial endometrioid adenocarcinoma.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, Nagoya, Japan. shiba@med.nagoya-u.ac.jp
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pubmed:publicationType |
Journal Article
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