rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
7
|
pubmed:dateCreated |
2004-6-23
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pubmed:abstractText |
The serum opacity factor (SOF) of Streptococcus pyogenes is a serotyping tool and pathogenesis factor. Using SOF-coated latex beads in cell adherence assays and antiserum directed against SOF in S. pyogenes-HEp-2 cell adherence inhibition experiments, we demonstrate SOF involvement in the fibronectin-mediated adherence of S. pyogenes to epithelial cells. SOF exclusively targets the 30-kDa N-terminal region of fibronectin. The interaction revealed association and dissociation constants 1 order of magnitude lower than those of other S. pyogenes fibronectin-binding proteins.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0019-9567
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
72
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4302-8
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:15213180-Binding Sites,
pubmed-meshheading:15213180-Cell Adhesion,
pubmed-meshheading:15213180-Epithelial Cells,
pubmed-meshheading:15213180-Fibronectins,
pubmed-meshheading:15213180-Humans,
pubmed-meshheading:15213180-Microscopy, Electron, Scanning,
pubmed-meshheading:15213180-Microspheres,
pubmed-meshheading:15213180-Peptide Hydrolases,
pubmed-meshheading:15213180-Streptococcus pyogenes
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pubmed:year |
2004
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pubmed:articleTitle |
Function of the fibronectin-binding serum opacity factor of Streptococcus pyogenes in adherence to epithelial cells.
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pubmed:affiliation |
Department of Medical Microbiology and Hospital Hygiene, University Hospital Rostock, Schillingallee 70, 18055 Rostock, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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