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rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2004-6-21
pubmed:abstractText
Quantitative trait loci for BW at 4, 6, 8, 12, and 18 wk of age were detected in an experimental F2 cross of layers divergently selected for primary antibody response to SRBC. A negative phenotypic correlation between levels of antibody titers and BW, was reported earlier within founder lines. The entire experimental population was genotyped with 174 microsatellite markers equally distributed over the genome. Two genetic models were applied in the QTL analysis: a half-sib model and a line-cross model, both using the regression interval method. In the half-sib model, 3 QTL for BW at 4 wk of age on chromosomes GGA2, GGA3, and GGA9 were detected. For BW at 6 wk of age, 3 QTL were detected on GGA2, GGA3, and GGA6. For BW at 8 wk of age, a QTL was detected on GGA7, and for BW at 12 and 18 wk of age, a QTL was detected on GGAZ. With the line-cross analysis model, one QTL on GGA7 for BW at 4 wk of age was detected. Two QTL were detected on GGA3 and GGA7 for BW at 6 wk of age, and one on GGA3 was detected for BW for 8 and 12 wk of age. For BW at 18 wk of age, there were no QTL under the line-cross analysis model. The present data suggest that 1) a different set of genes affects the early and the late growth, and 2) genes selected to humoral immune responsiveness are different from genes underlying growth.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0032-5791
pubmed:author
pubmed:issnType
Print
pubmed:volume
83
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
853-9
pubmed:dateRevised
2006-6-16
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Quantitative trait loci for body weight in layers differ from quantitative trait loci specific for antibody responses to sheep red blood cells.
pubmed:affiliation
Animal Breeding and Genetics Group, Wageningen Institute of Animal Sciences, Wageningen University, PO Box 338, 6700 AH Wageningen, The Netherlands. Maria.Siwek@wur.nl
pubmed:publicationType
Journal Article